Rarely (in less than 1-2% of cases) a malignant (cancerous) tumour (thyroid adenocarcinoma) can be the underlying cause of the disease. Nobody knows what causes hyperthyroidism, but the following factors have been noted as possible risk factors: Use of cat litter. Signs of hyperthryroidism. Less commonly, your thyroid can become overactive if lumps (nodules) develop on your thyroid. Nodules are usually non-cancerous (benign), but they may contain thyroid tissue, which can result in the production of excess thyroid hormones. It occurs when the immune system attacks the thyroid gland, causing it to enlarge and make too much thyroid hormone. Graves disease is the most common cause of hyperthyroidism. What causes hypothyroidism? This can occasionally happen if you're taking medicine that contains iodine, such as amiodarone, which is sometimes used to control an irregular heartbeat (arrhythmia). Rarely, hyperthyroidism is caused by a noncancerous tumor of the pituitary gland located at the base of the brain. The most common cause of hyperthyroidism is the autoimmune disorder Graves’ disease. An autoimmune disorder called Graves’ disease is the most common cause of hyperthyroidism. Toxic adenoma and toxic multinodular goiter are two other causes of hyperthyroidism that involve a strong genetic component. Causes of hyperthyroidism. In contrast, if you have hypothyroidism, you make too little thyroxine; this causes many of the body's functions to slow down.See the separate leaflet called Underactive Thyroid Gland (Hypothyroidism) for … Hyperthyroidism is another name for an overactive thyroid. Treatments for hyperthyroidism include antithyroid medications, radioactive ablation, and surgery. Rarely, it may be caused by a benign pituitary gland tumor which is located at the base of the brain. It is eight times more common in females than in males and often … What Are the Treatments for Hyperthyroidism? These lumps can make your thyroid grow bigger and produce too much T-4 hormone. This immune system disorder is the most common cause of hyperthyroidism. Plummer’s disease is more common in older people. … Doctors aren’t sure why some people get Graves’ disease, but it tends to run in families. The majority of cases occur as a result of Graves’ disease, a condition in which the immune system attacks the thyroid, causing it to produce too much thyroid hormone. Hyperthyroidism Guide: Causes, Symptoms and Treatment Options There are a number of conditions that can cause your thyroid to become overactive. Consumption of iodine in abundant amounts or using excessive amounts of thyroid hormone medication also cause hyperthyroidism. Thyroiditis is an inflammation of the thyroid gland. This can push your thyroid into overdrive for a short period of time. Hyperthyroidism causes a high metabolism, which has many negative effects on the body. In Graves’ Disease (also known as … Every aspect of your metabolism is regulated by thyroid hormones.Your thyroid gland produces two main hormones, thyroxine (T4) and triiodothyronine (T3), that influence every cell in your body. Most cases of an underactive thyroid are caused by the immune system attacking the thyroid gland and damaging it, or by damage that occurs as a result of treatments for thyroid cancer or an overactive thyroid. It causes thyroid hormones to leak into the blood, raising their overall levels and leading to hyperthyroidism. In more than 70% of cases, hyperthyroidism is caused by Graves’ disease. Hyperthyroidism has several causes, including Graves’ disease, thyroid nodules, and thyroiditis— inflammation of the thyroid. Graves' disease is the most common cause of hyperthyroidism, and can be associated with eye disease (Graves' opthalmopathy). It's not known why some people develop thyroid nodules, but they usually affect people over 60 years of age. Many other health problems can cause an overactive thyroid, for example, thyroiditis or taking too many thyroid hormones. Main causes of hyperthyroidism include Graves’ disease, thyroid nodules and thyroiditis. It’s important to work with your doctor to find the cause because it can affect your treatment. Weight loss, a high heart rate and high blood pressure are just a few of the common problems encountered by hyperthyroid cats. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Why Your Body Might Make Too Much Thyroid Hormone, The Thyroid (Human Anatomy): Picture, Function, Definition, Location in the Body, and More. This causes the gland to produce too much T-4 thyroid hormone. When the thyroid glands don’t produce enough hormone it’s known as hypothyroidism, or an underactive thyroid. Thyroiditis. An autoimmune disease causes it to attack your body’s tissues and/or organs. Another important hormone your thyroid produces is called calcitonin, and this helps keep a healthy amount of calcium in your blood. This results in high levels of the 2 main thyroid hormones, triiodothyronine (also called T3) and thyroxine (also called T4) in your body. These are called thyroxine (T-4) and triiodothyronine (T-3). About 3 in every 4 people with an overactive thyroid gland have a condition called Graves' disease. There can be a number of causes, including autoimmune disease, hyperthyroidism treatments, radiation therapy, thyroid surgery and certain medications.Your thyroid is a small, butterfly-shaped gland situated at the base of the front of your neck, just below your Adam's apple. Hypothyroidism can be caused by: Autoimmune thyroid disease – the most common cause. Hyperthyroidism and Graves’ disease. This is a disorder in which the immune system attacks the thyroid, causing overproduction of the thyroid hormone. Any of the following can cause hyperthyroidism: Autoimmune disease, such as Graves disease or Plummer disease Certain medicines, such as lithium, amiodarone, or aspirin If you have an overactive thyroid (hyperthyroidism), your thyroid gland produces too much of the thyroid hormones. Close menu, Back to Overactive thyroid (hyperthyroidism). Before exploring possible causes, though, it's important that you get a definitive diagnosis of hypothyroidism or hyperthyroidism, if you haven't done so already. There are three main causes of hyperthyroidism in the human body. It’s more likely to affect women under the age of 40. Graves’ disease is a hereditary condition (passed down through a family). Hyperthyroidism can be caused by a number of conditions, including Graves' disease, Plummer's disease and thyroiditis.Your thyroid is a small, butterfly-shaped gland at the base of your neck, just below your Adam's apple. Next review due: 24 September 2022, high levels of a substance called human chorionic gonadotrophin in your body – this can happen in early pregnancy, a, a pituitary adenoma – a non-cancerous (benign) tumour in the pituitary gland (a gland at the base of the brain that can affect the level of hormones produced by your thyroid). In some cases, hypothyroidism may be caused by genetic problems, leading to irregularities in hormone production. Hyperthyroidism is when your thyroid gland produces and secretes too many hormones and becomes overactive. Most people with hyperthyroidism develop hypothyroidism as medication causes the thyroid to go from overactive to underactive. It is an autoimmune condition. Some patients with Graves’ disease have an enlarged thyroid gland (a goitre). Other possible causes of an overactive thyroid include: Page last reviewed: 24 September 2019 At first, the symptoms may be mistaken for simple nervousness due to stress. All rights reserved. Graves' disease This is the most common cause of hyperthyroidism in iodine-sufficient areas, accounting for about 80% of cases. Two major hormones that affect how your body works are produced in your thyroid. This accounts for 70% of the cases. Normally, the antibodies in your blood go after bacteria, but if you have Graves’ disease, the antibodies turn on your thyroid instead. Toxic adenoma occurs when a single nodule on the thyroid gland causes increased thyroid hormone production. It causes antibodies to stimulate the thyroid to secrete too much hormone. These medical conditions can include: Graves’ disease: In this disorder, your immune system attacks the thyroid. Graves’ disease … Graves’ disease. Graves' disease is an inherited disease (which affects several family members) and is more frequently found in women than in men. The underlying cause is unknown but in rare cases cancer can cause the condition. Mayo Clinic: “Hyperthyroidism (overactive thyroid).”, American Thyroid Association: “Hyperthyroidism (Overactive).”. The recommendation to check TSH-receptor antibodies (TRAbs) to distinguish Graves' disease from other causes of hyperthyroidism is based on the NICE clinical guideline , the ATA guidelines on hyperthyroidism , the ETA guideline on Graves' hyperthyroidism [Kahaly, 2018], and expert opinion in review articles [De Leo, 2016; Kravets, 2016; Bathgate, 2018; Biondi, 2018]. An overactive thyroid that's caused by a medicine will usually improve once you stop taking that medicine, although it may take several months for your thyroid hormone levels to return to normal. Graves' disease is an autoimmune condition where your immune system mistakenly attacks your thyroid which causes it to become overactive. There… Other conditions linked to hyperthyroidism include: Plummer’s disease. Hyperthyroidism means an overactive thyroid gland.When your thyroid gland is overactive it makes too much thyroxine. This is thought to be due to varying levels of iodine in the diet. Smoking can also increase your risk of getting it. When your thyroid doesn't produce enough hormones, the balance of chemical reactions in your body can be upset. Graves’ disease is the most common cause of hyperthyroidism, accounting for over 70% of cases. It was named after Robert Graves, an Irish physician, who described patients with this condition in the 19th century. Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. If you have been trying to lose weight by dieting, you may be pleased with your success until the hyperthyroidism, which has quickened the weight loss, causes other problems. It’s when the butterfly-shaped gland in your neck produces too much thyroid hormone. It … The underlying cause of this change is currently unknown, but is very similar to one of the two main causes of hyperthyroidism in humans called ‘toxic nodular goitre’. There are several different medical conditions that can cause hyperthyroidism. © 2005 - 2021 WebMD LLC. Symptoms appear slowly, so you may not notice a problem at first but left untreated over a long period, hyperthyroidism can be fatal. The thyroid gland makes the hormones thyroxine (T4) and triiodothyronine (T3) that play an important role in the way your whole body functions. Menu This can occasionally happen if you're taking medicine that contains iodine, such as amiodarone, which is sometimes used to control an irregular heartbeat (arrhythmia). 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